Clostridium botulinum toxin poisoning in dogs and cats
Clostridium botulinum toxin poisoning in dogs and cats
Clostridium botulinum toxin poisoning disease,. Mildly ill chickens are paralyzed in both legs, unable to walk, and some wings droop; in severe cases, the head and neck are straightened and rested on the ground, unable to be lifted, so it is also known as soft neck disease.
[Clinical Symptoms]
Clostridium botulinum toxin toxicosis is a toxic disease that occurs mainly due to ingestion of the neurotoxin, clostridium botulinum toxin, produced by Clostridium botulinum in carcasses of decaying animals or feed. It is characterized by motor central nerve paralysis and medullary paralysis. Symptoms of Clostridium botulinum toxin poisoning in animals are related to its severity depending on the amount of toxin ingested into the body and the sensitivity of the animal. The incubation period of the disease is 4~24 hours, the initial symptoms of the dog for the occurrence of progressive, symmetrical limb paralysis, generally from the hind limbs to extend forward, and then cause tetraplegia, but at this time, the tail can still swing. Affected dogs have decreased reflexes and reduced muscle tone, showing obvious signs of motor neuropathy. Botulinum toxin poisoning occurs in the sick dog body temperature is generally not high, conscious. Due to the weakening of jaw muscle tone, it can cause jaw droop, difficulty in swallowing and salivation. In severe cases, both ears droop, poor eyelid reflexes, visual disturbances and dilated pupils. Sometimes conjunctivitis and ulcerative keratitis are seen. In severely poisoned dogs, there is dyspnea, rapid and disturbed heart rate, constipation and urinary retention due to decreased tone of the abdominal muscles and diaphragm. Dogs that develop Clostridium botulinum toxin poisoning have a high mortality rate and generally take a long time to recover, if at all.
[Treatment Program]
The principles of treatment are detoxification and rehydration.
[Prescription 1] Antitoxin type C, dogs: 3 to 5 ml, intramuscular or intravenous.
[Prescription 2] Botulinum toxin antitoxin type A, canine: 10,000 units, and botulinum toxin type B: 10,000 units mixed and injected intramuscularly at intervals of 5 to 10 hours, repeated once.
[Prescription 3] 5% dextrose injection, Ringer’s solution, 25% vitamin C injection, mixed and injected intravenously once a day for 2 days.