Multiple myeloma in dogs and cats
Multiple myeloma in dogs and cats
Canine and feline multiple myeloma is a malignant tumor originating from plasma cells that occurs rarely in dogs and cats. Canine and feline multiple myeloma arises mainly from tumorigenic invasion of the bone marrow and other sites and overproduction of immunoglobulins, and the clinical signs generally vary depending on the etiology.
Clinical signs of multiple myeloma in dogs and cats
Multiple myeloma in dogs and cats occurs, on average, in dogs aged 5.5 to 9.2 years and cats aged 8.3 to 9.3 years, with cats presenting slightly more cases than dogs. Symptoms include lameness, bone pain, weakness, and pathologic fractures. Anemia, abnormal bleeding, palpable masses, depression and weightlessness are also seen. Cats also have pale mucous membranes, fever and chronic infections.
Nerves are compressed by the tumor resulting in neurological abnormalities including hemiparesis or paralysis.X-rays show generalized long bones, ribs, vertebrae, and skull with multiple or isolated osteolysis or generalized osteoporosis. Blood tests reveal normocytic, normochromic anemia. Mature and naïve plasma cells were commonly seen on bone marrow aspiration. Total serum protein is significantly elevated.
Dr. Oxygen Pet recommends
1, canine and feline multiple myeloma is often fatal, can not be cured by surgery or drugs, currently in addition to taking anti-tumor drugs chemotherapy, but also need to control complications.
2, affected dogs and cats with symptoms of infection and fever, you can take Vipda Amoxicillin Powder orally, anti-inflammatory and antibacterial, once a day, for 3-5 days.
3、Fenmeclo Meloxicam Tablets (Puente) joint anti-inflammatory pain reliever, can be used to relieve bone pain, adjusting the symptoms of lameness in dogs and cats. 0.1 mg / kg body weight, once a day, the first time to double.
Treatment Options for Multiple Myeloma in Dogs and Cats
Treatment is based on chemotherapy and prevention of secondary infections.
1. Cyclophosphamide, 2 mg/kg, every other day/one time daily, orally.
2, Vincristine, 0.02~0.05 mg/kg, once in 7~10 days, intravenous drip.
3. Isocyclophosphamide, 9~10 mg/kg, once in 2~3 weeks, intravenous drip.
4. Cisplatin, 1.5~1.75 mg/kg once daily for 5 days intravenously.
5. Penicillin, 20,000 units/kg, 2-3 times daily, intramuscular or intravenous.
6. Kanamycin, 5-15 mg/kg, 2-3 times daily, intramuscular injection.